Ribose modification Ribose modification is another common strategy that has had notable success
The human data, while limited by sample size (n=20-40 across studies), documented measurable outcomes: Photoaging reversal: In a 12-week facial application study, participants using 2% GHK-Cu cream showed mean improvement scores of 4.8/10 in skin laxity, 5.6/10 in fine wrinkle depth, and 6.2/10 in overall photoaging appearance on physician-graded scales
Back Mojsov, S, Weir, GC, Habener, JF (Feb 1987) 'Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas', Journal of Clinical Investigation , 79, 616-19
NASH is the progressive form of NAFLD, characterized by hepatocyte death and hepatic inflammation